Laboratory for GPCR Signaling in Epithelial Physiology
Department of Otorhinolaryngology–Head and Neck Surgery
Division of Rhinology
University of Pennsylvania Perelman School of Medicine
Philadelphia, PA USA
May 10, 2018
Bacterial quinolones and bitter receptors
Thanks to everyone involved in our newly accepted J Biol Chem paper. It has lots of live cell imaging of calcium indicators and fluorescent protein biosensors to look at signaling in response to T2R activation by a class of bacterial quorum-sensing ligands, quinolones, going from heterologous expression to primary differentiated air-liquid interface cultures. Jenna is off to grad school at Einstein for neuroscience this summer, so it’s nice to get this one accepted before she leaves the lab.